Informations

17septembre

Malaria therapy and prophylaxy with unsaturated fatty acids

PUFA Malaria

Artemisia plants are rich in polyunsaturated fatty acids (PUFA) which generate prostaglandins and stimulate monocytes. PUFAs possess well documented antimalarial and prophylactic properties. Their half-life in plasma is several days and in adipose tissue several weeks. This may explain the prophylactic effect of regular consumption of Artemisia infusion or powder. Fish oils rich in polyunsaturated fatty acids (PUFAs) cause a marked in vitro growth inhibition of Plasmodia. Similar effects were seen in vivo on mice infected with...

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13septembre

Fish oil against malaria

Arginine nitric oxide

In 1957 the University of London found that dietary cod liver oil suppressed the multiplication of Plasmodium berghei in mice D.G. Godfrey, Antiparasitic action of dietary cod liver oil upon Plasmodium berghei and its reversal by vitamin “E” Experimental Parasitology Volume 6, Issue 6, November 1957, Pages 555-56 of Babesia rodhaini D.G Godfrey The influence of dietary cod liver oil and vitamin E upon Babesia rodhaini in mice Experimental Parasitology Volume 6, Issue 6, November 1957, Pages 555-565 and on Trypanosoma...

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13septembre

The antimalarial properties of milk

breastfeeding against malaria

It all begins in 1952 with the work of the Liverpool School of Tropical Medicine B. G. Maegraith, T. Deegan, and E. Sherwood JonesSuppression of Malaria (P. Berghei) by Milk. Br Med J. 1952 Dec 27; 2(4799): 1382–1384. Audrey A. N. Keppie. Modified Course of T. congolense Infection in Mice Given Diets with Milk Casein. Br Med J. 1953 Oct 17; 2(4841): 853–857. They found that in rats inoculated with Plasmodium berghei and living on a diet of milk there was a strong suppression of the growth of the parasites. This was valid for...

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11septembre

malaria transmission is enhanced by antibiotics

antibiotics and malaria: dangerous mix

Some over the counter drugs sold on a large scale in Africa, show strong antagonism with several antimalarial drugs. Aspirin has an effect on the endothelium and platelet adherence. The time to parasite clearance is significantly longer in children treated with paracetamol and recrudescence is higher. This of course does not prevent the swamping of Africa with these commodities by Bigpharma. You don’t kill a cash cow even if the collateral damage is the death of thousands of children! And now it is also confirmed that antibiotics...

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11septembre

Antimalarials and antiretrovirals are antagonistic

Antiretrovirals bad for malaria

At the 15th International Workshop on Clinical Pharmacology of HIV on May 19, 2014 at the University of Nebraska, it was shown that nevirapine co-prescribed with artemether-lumefantrine may reduce the artemether concentration in blood by 70%. Fehintola FA, Huanf L, Scarsi KK, Darin KM, Parikj S. Reduced artemether-lumefantrine exposure in HIV-infected Nigerian subjects on nevirapine-based antiretroviral therapy. 15th International Workshop on Clinical Pharmacology of HIV&Hepatitis Therapy Fehintola FA, Scarsi KK, Ma Q, Parikh S, Morse...

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Citation

L’homme nous passionne, sa diversité, ses histoires, ses savoirs, ses ignorances, sa compréhension du monde

Alexandre Poussin

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