Submitted by Pascal Gisenya and Pierre Lutgen on 12/06/2021 In 2014, the blog « Artequick programmed for failure » on www.malariaworld.org had started a heated debate. Meanwhile several mass drug administration trials have failed, the largest one performed in the Comoros by a Chinese company. This does not prevent other people to use Africans as guinea pigs for further mass drug administration trials with the same ACTs. Okebe, J., Dabira, E., Jaiteh, F. Koen Peeters Grietens & Umberto D’Alessandro. Reactive, self-administered...

Submitted by Pascal Gisenya and Pierre Lutgen on 12/06/2021 In 2014, the blog « Artequick programmed for failure » on www.malariaworld.org had started a heated debate. Meanwhile several mass drug administration trials have failed, the largest one performed in the Comoros by a Chinese company. This does not prevent other people to use Africans as guinea pigs for further mass drug administration trials with the same ACTs. Okebe, J., Dabira, E., Jaiteh, F. Koen Peeters Grietens & Umberto D’Alessandro. Reactive, self-administered...

Pascal Gisenya, Nsengiyumva Bati Daddy, Jérôme Munyangi, Mutaz Akkawi, Pierre Lutgen Already 30 years ago it was known that human monocytes which have ingested hemozoin are unable to neutralize pathogenic bacteria, fungi, and tumor cells, and that macrophage responses decline during the course of human and animal malaria. Hemozoin (Hz) is a biocrystal synthesized by Plasmodium and other blood-feeding parasites to avoid the toxicity of free heme derived from the digestion of hemoglobin during invasion of the erythrocytes. Schwarzer...

Pascal Gisenya, Nsengiyumva Bati Daddy, Jérôme Munyangi, Mutaz Akkawi, Pierre Lutgen Already 30 years ago it was known that human monocytes which have ingested hemozoin are unable to neutralize pathogenic bacteria, fungi, and tumor cells, and that macrophage responses decline during the course of human and animal malaria. Hemozoin (Hz) is a biocrystal synthesized by Plasmodium and other blood-feeding parasites to avoid the toxicity of free heme derived from the digestion of hemoglobin during invasion of the erythrocytes. Schwarzer...

A few years ago we described in a blog on www.malariaword.org the role zinc may have in diarrhea and tropical diseases. Zn2+ deficiency is a common comorbidity of many chronic diseases. In a recent weblog we describe the deleterious effect of zinc deficiency in elderly people on the development of pneumonia. Zinc deficiency has a detrimental effect on blood pressure and hypertension is one of the major causes of mortality in Covid infections. A systematic review and meta-analysis of randomized clinical trials on the effects of zinc...