Quand la Sorbonne confirme les travaux des chercheurs africains

Un important article scientifique vient d’être publié par une équipe de chercheurs de la Sorbonne. Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites Kutub Ashraf, Dominique Mazier et al . doi.org/10.1101/2021.08.10.455849 bioRxiv …..Recently the use of traditional infusions from Artemisia annua (from which artemisinin is obtained) or A. afra (lacking artemisinin) has been controversially advocated….. Here, we conducted the first comparative study of the anti-malarial effects of both plant infusions in vitro against the asexual erythrocytic stages of P. falciparum and the pre-erythrocytic (i. e., liver) stages of various Plasmodium species. Low concentrations of either infusion accounted for significant inhibitory activities across every parasite species and stage studied. We show that these antiplasmodial effects were essentially artemisinin-independent and were additionally monitored by observations of the parasite apicoplast and mitochondrion. In particular, the infusions significantly incapacitated sporozoites, and for P. vivax and P. cynomolgi, disrupted the hypnozoites….. Cet article confirme dans une large mesure ce qu’avaient mis en en évidence nos partenaires congolais dans leurs travaux sur le terrain Constant Kansango Tchandema MD, Pierre Lutgen PhD, In vivo trials on the therapeutic effects of encapsulated Artemisia annua and Artemisia afra, GJRA, 2016, 5,6, pp 228-234 ISSN 2277-8160 Jerome Munyangi and Michel Idumbo, Breaking news from clinical trials with Artemisia plants. www.malariaworld.org, Jan, 2016 D’autres chercheurs africains ont fait au moins une dizaine d’essais cliniques qui montrent que les décoctions de Artemisia afra non seulement guérissent le paludisme, mais sont également prophylactiques et arrêtent la transmission. Elles élimininent non seulement les mérozoïtes mais également les gametocytes. L’éradication de la malaria en Afrique devient possible